Animals
The animals used in this experiment were in line with the “Guidelines
for the Care and Use of Laboratory Animals” formulated by Shandong
Province, China, and approved by Medical Ethics Committee for
Experimental Animals, Shandong University School of Basic Medicine
Sciences (ECAESDUSM 2014056). We separated wild-type C57BL6/J mice
(male, 6–8 weeks of age) randomly. The investigators were blinded to
the group allocation. Animals were euthanized by cervical dislocation
after DSS administration.