Reporting of the included studies – RECORD (Figure 3):
The median completeness score was 87% (interquartile range 82–92%)
and only one study scored 100%. A large proportion of studies did not
describe/outline the study design, either in the abstract (56 studies,
45% - Item 1A) or in the methods 4 (37 studies, 29% - Item 4). Despite
the fact LTOT definition was stated, 14 studies (11% - Item 7) did not
provide enough detail to allow the replication of results or provided
inconsistent definitions in the abstract/methods. In addition, 37
studies did not specify which opioids were considered in the analysis
(29% - Item 7.1). Other methodological areas of underreporting included
how missing data and loss to follow-up were addressed (77 studies and 48
studies, Items 12C and 12D, respectively).