Conclusion
This study highlights that age, BMI, E2, and number of follicles ≥12mm
at trigger can predict oocyte yield in SEF cycles. As such,
individualising SEF cases with consideration of these markers, should be
undertaken to optimise oocyte yield. AMH and AFC are however not
independently significantly associated with oocyte yield. Additionally,
this is the first study to establish an incidence of OHSS in SEF cycles
and establish a significant relationship between age, total AFC, number
of follicles ≥12mm and FSH as predictors of OHSS. Moreover, the
reproductive outcomes presented highlight that undertaking SEF over the
age of 40 years is suboptimal and associated with a low chance of
success. Whilst there was no significant difference in livebirth rates
in women ≤35 years and aged 36-39, it is advisable that SEF should be
undertaken at or prior to the age 36 to optimise outcomes. This data has
significant implications for clinical practice, and can be used to
individualise care, enhance counselling and manage expectations in women
undergoing SEF.