Figure 2
IgE-IC processing by CD23. CD23a and CD23b are expressed in epithelial cells (A) which mediate endocytosis, transcytosis and release of the chemokine CCL20 in response to CD23 triggering; in human primary B cells (B) which mediate endocytosis, recycling and transport and in EBV B cells (C) which are capable of antigen degradation and IgE-facilitated antigen-presentation (FAP). In dendritic cells (D) only CD23b is expressed which mediates phagocytosis, antigen degradation and antigen presentation in cooperation with B cells.