Figure 4
CD23 as an inhibitor of allergic sensitisation. CD23 plays different roles during the allergic response including A) clearance of serum IgE that counteracts the allergic pathway to prevent IgE sensitization on FcɛRI B) negative feedback regulation of IgE synthesis by binding of IgE-ICs to CD23 on B cells C) T cell proliferation and antibody production induced by binding of IgE-ICs to CD23 on B cells.