FIGURE 5: The phylogenetic networks of MHC class I of four
species of turdidae family along with homologues sequences from
passerines species. GenBank accession number are provided. Species name
are mention lower right side with branch colors. Neighbor-Net networks
based on uncorrected P -distances and carried out
1000
bootstrap replicates to estimate nodal
support.
Nodal support values
(> 75%) were displayed.
CONCLUSION
Our study shows that species of Turdidae family has retained
significant MHC class I diversity, which supports high conservational
value and contribute to evolution of MHC class I genes. Importantly, we
specifically amplify the exon 3 locus, provide an opportunity to avoid
chimera formation during molecular characterization of hypervariable
genes of immunity. At the same time, our study is the first to validate
contrasting patterns of allelic diversity and positive selection upon
inferred PBR and non-PBR codons supported the hypothesis that different
mechanisms can shape evolutionary paths of MHC class I.