The concentrations of soluble CXCL16 were increased in the
patients with sepsis
In the serum of 55 septic patients, admission levels of soluble CXCL16
were significantly increased than those of healthy individuals (Figure
1A). Soluble CXCL16 levels were still significantly elevated on day 7
compared with healthy individuals (Figure 1B). Soluble CXCL16
concentrations were significantly higher in septic shock patients
compared to septic patients without shock (Figure 1C), and non-surviving
patients with sepsis displayed significantly increased CXCL16 levels
compared to survivors (Figure 1D). However, there was no statistical
difference in circluating CXCL16 concentrations between bacteremia
patients and non-bacteremic patients on ICU admission (Supplementary
Figure 1).