The concentrations of soluble CXCL16 were increased in the patients with sepsis
In the serum of 55 septic patients, admission levels of soluble CXCL16 were significantly increased than those of healthy individuals (Figure 1A). Soluble CXCL16 levels were still significantly elevated on day 7 compared with healthy individuals (Figure 1B). Soluble CXCL16 concentrations were significantly higher in septic shock patients compared to septic patients without shock (Figure 1C), and non-surviving patients with sepsis displayed significantly increased CXCL16 levels compared to survivors (Figure 1D). However, there was no statistical difference in circluating CXCL16 concentrations between bacteremia patients and non-bacteremic patients on ICU admission (Supplementary Figure 1).