Admission levels of CXCL16 correlated with disease severity in the patients with sepsis
Serum soluble CXCL16 levels were significantly correlated with SOFA scores on day of ICU admission (Figure 2A). Moreover, admission levels of soluble CXCL16 correlated with WBC numbers (Figure 2B) and the concentrations of CRP (Figure 2C).
To investigate whether soluble CXCL16 levels are correlated with other cytokine levels in the serum of patients with sepsis, we also assessed the serum concentrations of IL-6, IL-8, IL-27 and TNF-α. Soluble CXCL16 levels and levels of cytokines including IL-6, IL-8, IL-27 and TNF-α were significantly correlated at day of ICU admission (Supplementary Table 4).