Figure legends
Figure (1) Maximum angle of knee extension with zero degree represent as the maximum possible extension (Rezende et al., 2006)
Figure (2) : The histopathological findings of different groups. I : Non-osteoarthritic group showing articular cartilage (AC) with its smooth surface (arrow). The chondrocytes appear in the matrix (curved arrow). Subchondral bone (B) and bone marrow (BM) are seen, allocated Grade-0. IIa : OA group showing marked erosion of articular cartilage surface with marked matrix loss (arrow), decreased number and size of chondrocytes with some cell death (curved arrow) and some cavities in the subchondral bone (asterisk), allocated Grade-4. IIb : OA group showing irregular surface (arrow), disorientation of chondrocytes with some cell death (arrowhead) and presence of multiple cavities (asterisk), allocated grade 3.III : Glucosamine treated OA group: Showing discontinuous superficial layer of articular cartilage (arrow), increase in the number of chondrocytes, with cluster formation (arrowhead), some cell death (asterisk), matrix loss (tailed arrow) and increase in cartilage thickness, allocated Grade-2 (Group 3, H & E X 400). IV : diacerein treated OA group showing an irregular surface of articular cartilage (arrow), increase in the number of chondrocytes, disturbed morphology with cluster formation (arrowhead), some cell death (asterisk) and increase the cartilage thickness, allocated Grade-2.V : atorvastatin treated OA group showing a nearly smooth surface of articular cartilage (arrow), a slight increase in the number of chondrocytes with the initiation of cluster formation, condensation of cells in the superficial layer (arrowhead) and increase the cartilage thickness, allocated Grade-1. (H&E, X400).