Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma
Nazanin Zounemat Kermani1*, Woo-Jung Song2, 3*, Yusef Badi1,2, Ali Versi1,2, Yike Guo1, Kai Sun1, Pank Bhavsar2, Peter Howarth4, Sven-Erik Dahlen5, Peter J Sterk6, Ratko Djukanovic4, Ian M Adcock1,2, Kian Fan Chung1,2 on behalf the U-BIOPRED Consortium
1Data Science Institute, Imperial College London, United Kingdom; 2National Heart & Lung Institute, Imperial College London; 3Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 4Faculty of Medicine, Southampton University, Southampton, UK and NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK; 5Centre for Allergy Research, Karolinska Institute, Stockholm, Sweden; 6Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
*Contributed equally.
Running title : ACE2, TMPRSS2 and FURIN in severe asthma