Product Quality Analysis
The harvested cultures of fed-batch samples were purified by either
one-step protein A chromatography capture (shake flask samples) or WuXi
Biologics downstream platform (manufacturing samples). Purified samples
were subjected to WuXi Biologics platform analytical methods, such as
Size Exclusion Chromatography (SEC), imaged Capillary Isoelectric
Focusing (iCIEF), and N-Glycan LC.