2.5 End points and their definition
The first end points included LC. LC was defined as the interval from the date of RSI-BT to the date of local progression. The second end points included OS and treatment-related toxicity. OS was defined as interval from the date of RSI-BT to the date of death for any cause. Treatment-related toxicity was evaluated by the Radiation Therapy Oncology Group (RTOG) classification criteria28.