Table 4. Adjusted analyses for associations between geohelminths, geohelminth parasite species and parasite burdens in mothers and children and wheeze/asthma in later childhood, stratified by presence (+) and absence (-) of allergen skin prick test reactivity.
SPT – allergen skin prick test reactivity to any of 9 allergens (SPT+, n=1649; SPT-, n=284). Odds ratios (OR) and 95% confidence intervals (95% CI) were estimated using logistic regression and adjusted for maternal allergy and ethnicity, area of residence, sex, birth order, contact with large farm animals, geohelminths in the child to 5 years (for maternal geohelminths), maternal geohelminths (for childhood geohelminths), and presence of other species of geohelminth parasite. P<0.05 are shown in bold. Interaction P values are shown for adjusted models but did not differ markedly from those of unadjusted models. Infection intensity categories are: A. lumbricoides , light (<5,000 epg), moderate/heavy (>5,000 epg);T. trichuira , light (<1000 epg), moderate/heavy (>1,000 epg). Denominators for geohelminth prevalence versus intensity results differ because it was not possible to do Kato-Katz examinations on all samples where sample volume was insufficient. P<0.05 are shown in bold.