Table 4. Adjusted analyses for associations between geohelminths,
geohelminth parasite species and parasite burdens in mothers and
children and wheeze/asthma in later childhood, stratified by presence
(+) and absence (-) of allergen skin prick test reactivity.
SPT – allergen skin prick test reactivity to any of 9 allergens (SPT+,
n=1649; SPT-, n=284). Odds ratios (OR) and 95% confidence intervals
(95% CI) were estimated using logistic regression and adjusted for
maternal allergy and ethnicity, area of residence, sex, birth order,
contact with large farm animals, geohelminths in the child to 5 years
(for maternal geohelminths), maternal geohelminths (for childhood
geohelminths), and presence of other species of geohelminth parasite.
P<0.05 are shown in bold. Interaction P values are shown for
adjusted models but did not differ markedly from those of unadjusted
models. Infection intensity categories are: A. lumbricoides ,
light (<5,000 epg), moderate/heavy (>5,000 epg);T. trichuira , light (<1000 epg), moderate/heavy
(>1,000 epg). Denominators for geohelminth prevalence
versus intensity results differ because it was not possible to do
Kato-Katz examinations on all samples where sample volume was
insufficient. P<0.05 are shown in bold.