p values: Log Rank Test.
High risk patients were further analyzed for the factors affecting
biochemical recurrence free survival with multivariate analysis. Cox
regression analysis including patients’ waiting period, PSA value at the
time of diagnosis, Gleason grade groups in prostate biopsy and radical
prostatectomy specimens, presence of positive surgical margins and/or
having SV invasion demonstrated the main factor affecting time to PSA
progression in high risk patients as SV invasion (p<0.001
HR:2.51 CI: 1,58-4,45). Other factors including time to surgery(p=0.156
HR:0.63 CI:0.33-1.19) did not have any statistically significant impact
on outcome.