Process of care assessments
Process of care assessments are as follows:
- Time from hospital admission to randomisation
- Total cumulative dose of nebulised heparin
- Days of treatment with nebulised heparin
- Mean daily APTT among all participants, and among those treated with intravenous or subcutaneous unfractionated heparin, and among those not treated with intravenous or subcutaneous unfractionated heparin
- Highest APTT among all participants, and among those treated with intravenous or subcutaneous unfractionated heparin, and among those not treated with intravenous or subcutaneous unfractionated heparin
- Days of treatment with each of the following therapies while in the study: unfractionated heparin, IV and SC; LMWH, IV and SC; lopinavir-ritonavir; remdesivir; hydroxychloroquine; interferon-β; interleukin antagonists; oseltamivir, laninamivir, zaninamivir or peramivir; macrolide; non-macrolide antibacterial; antifungal; corticosteroid; inotrope or vasopressor infusion; and renal replacement.