Differences between SLE patients and healthy subjects
We observed a significant increase in the frequency of expression of
cell activation and exhaustion markers in both the CD4+ and the CD8+
compartment between the SLE patients and HS group. The T cell
subpopulations in SLE patients presented an increase in the frequency of
PD-1, CD57, EOMES, and exhausted and activated populations when compared
with the HS group. Table 4 and Figure 2 shows all the populations that
were identified as differentially expressed between groups.