Main findings
To the best of our knowledge, this is the first study to estimate
the
association between ApoB, ApoB/ApoA-1 ratio during mid-pregnancy and the
risk of PTB. We found that maternal mid-pregnancy ApoB level and
ApoB/ApoA-1 ratio were positively
related to the risk of PTB. In addition, these associations showed a
linear dose-response relationship. Subgroup analysis suggested that the
effect of ApoB/ApoA-1 ratio might be more relevant among
women with pre-pregnancy
BMI
≤ 24 kg/m2, age at delivery ≥ 35 years or those who
were multiparous.