2.2 Antigenicity and hydrophilicity analyses of NTD of G1 and G2 PEDV S protein
Antigenicity and hydrophilicity analyses based on the amino acid sequence from 1 to 380 at N-terminal of S proteins of PEDV Chinese variant and CV777 vaccine strain were carried out by using Protean software of DNAStar Lasergene (DNAStar, Inc., Madison, WI). Antigenic indexes of the N-terminal domains (NTD) were calculated under the Jameson-Wolf method, and hydrophilicity plots were constructed by Kyte-Doolittle method, respectively.