Acknowledgements
The authors thank Dr Lewis Green (Salford Royal Foundation Trust)
assisting with data collation.
Transparency statement
Dr. Heald as corresponding author affirms that this is an honest,
accurate, and transparent account of the study being reported; that no
important aspects of the study have been omitted; and that any
discrepancies from the study as planned (and, if relevant, registered)
have been explained.
Ethics Statement
As this project was deemed by our local Research and Development
Committee as a quality improvement (QI) project, no individual patient
was contacted in the course of the evaluation and data was fully
anonymised prior to analysis, it was not felt that formal ethics
permission was required.
Funding
We have no external funding to declare.
Role of the Sponsor
There was no research sponsor for this study
Dissemination of study results to
participants
Dissemination to interested patient groups both locally and nationally
will be done once the analysis has been finalised
Patient Consent
This was not deemed necessary as no individual patient was contacted or
asked to do anything beyond their usual clinical care.
Data Availability
We used patient level data which was fully anonymised prior to analysis.
Any requests for access to this data should be made to the corresponding
author, Dr Adrian Heald.
Duality of interest
No author has anything to disclose in relation to conflict of interest.
Contribution Statement
AHH and AR conceived the study. MM and LM collected the data. MM, AAF
and GY conducted the data analysis. CJD, ML and AAF provided perspective
from the laboratory. AN assisted with the literature review.
MM, LM, GY, ML, SD, AR, AN, AAF, CJD, PT and AHH all contributed to
writing of the paper. AAF, and PT provided an overview of the
manuscript.