Associations between endotypes and responses to surgical and medical treatments
Few studies have been performed evaluating the efficacy of specific treatments for CRS as a function of endotype. Outcome studies for CRS have generally not evaluated endotype prior to intervention, relying on phenotype to subdivide patients. Further, the definition of treatment success and the time point of evaluation post intervention have also been variable. Despite these limitations, some tentative statements can be made based on the presumed endotype of the population treated.