Funding:
This study was funded by an MRC ‘Mechanism of human disease’ grant in
collaboration with AstraZeneca (Grant Ref: MR/K015141/1). JAS is funded
by the NIHR Manchester Biomedical Research Centre, a Wellcome
Investigator in Science Award and is an NIHR Senior Investigator. HB is
funded by a North West Lung Centre Pickering Fellowship. I.S currently
supported by the European Respiratory Society RESPIRE 3 Marie Curie
Fellowship Award (EU Horizon 2020 713406). I.S also reports grants from
BMA James Trust Award, North West Lung Centre Charity, personal fees
from Educational Talks for GPs, Travel Award for Conference Meetings,
outside the submitted work.