Calculation of additive interaction index of depression and
hypertension on quality of life
As shown in Table 3, the reference is no depression and no hypertension.
The OR value of non depression with hypertension on quality of life was
0.913 (95%CI: 0.492-1.695); the OR value of depression without
hypertension on quality of life was 8.442 (95%CI: 5.666-12.578); the OR
value of depression with hypertension on quality of life was 11.846
(95%CI: 6.597-21.271). In table 4, the confidence interval of RERI and
AP was greater than 0, and the confidence interval of S was greater than
1, which indicated that depression and hypertension had additive
interaction on the occurrence of poor quality of life in patients with
gynecological tumor (this was a synergistic effect). AP was 0.295,
indicating that 29.5% of the patients with poor quality of life due to
the interaction between depression and hypertension. According to Table
5 and Table 6, we can also draw the conclusion that the OR value of non
anxiety with hypertension on quality of life was 0.844 (95%CI:
0.480-1.483); the OR value of anxiety without hypertension on quality of
life was 6.630 (95%CI: 4.527-9.711); the OR value of anxiety with
hypertension on quality of life was 10.297 (95%CI: 5.647-18.775).
Anxiety and hypertension had additive interaction on the occurrence of
poor quality of life in patients with gynecological tumor (this was a
synergistic effect). 37.1% (AP=0.371) of the patients with poor quality
of life due to the interaction between anxiety and hypertension.