[Key words]
Liver failure; Spontaneous splenic rupture; Light chain amyloidosis;
Congo red staining
The pathological mechanism for amyloidosis is as follows: Amyloid
deposits between the cells in various organs, which may lead to
dysfunction of the cells, and eventually cause failure of the affected
organs [1]. Amyloid is essentially a protein
binding to mucopolysaccharides, which turns blue when exposed to iodine,
just the same as starch. It is not tissue or organ specific, and may be
found anywhere in the body. Therefore, relevant clinical manifestations
are complicated, and easy to be misdiagnosed. There following is a
report concerning a case of light chain systemic amyloidosis manifested
as liver failure complicated with fatal spontaneous splenic rupture, who
was treated in our department.