Relationships of fungal status with changes in lung function
Average rate of ppFEV1 decline during follow-up was not
statistically different between the frequent fungi group compared to the
rare group (-1.85% versus -1.61% per year respectively, figure S2).
Using regression modeling, there was no difference between fungal
groups, even when controlling for ABPA, chronic P. aeruginosa ,
and transitioning across groups. Interestingly, in this model, when
comparing only those with ABPA and frequent fungal infection to those
with ABPA and rare fungal infection, fungal status was significant,
showing that those with ABPA and frequent fungal infection had lower
lung function at each time point compared to those with ABPA and rare
fungal infection (p = 0.047).