Figure 7. Compound 270 relieves the mice acute lung injury
triggered by intraperitoneal injection of LPS through eliminating lung
inflammation state
(A) Histological assessment of lung tissues was evaluated by HE
staining. Scale bar = 200 μm, (n = 6). (B) The relative mRNA levels of
pro-inflammation genes in lung tissues were quantified by RT-PCR
normalized by GAPDH, (n = 6). (C) The protein expression of NF-κB and
JNK signaling pathways in lung tissues was measured by western blot
analysis, (n = 6). (D) Quantification of the relative protein expression
shown in (C) was performed by densitometric analysis, (n = 6). The data
are presented as the means ± SEM. One-tailed Student’s t-test. *P
< 0.05, **P <0.01, ***P < 0.001 compared
with the LPS group.
Figure 8