Conclusion
The findings of the present meta-analysis do not support a significant
increase of serum LDH in hypertensive disorders of pregnancy with the
exception of patients with that develop severe preeclampsia. Even in
this latter group, however, the actual diagnostic accuracy of the enzyme
seems to be limited by the scarce available evidence. Its predictive
accuracy in determining adverse maternal and neonatal outcomes is
extremely limited and is mainly based in pregnant women that develop
hemolysis. Future research should expand in this field, rather than
assessing differences in serum LDH values among the various subgroups of
hypertensive disorders of pregnancy.