ETHICAL APPROVAL
Approved by the ethics committee in Stockholm: 2013/827-31/3, 2014/1980-32, 2016/1390-32, 2020-00807 and the Swedish Drug Agency: 5.1-2013-46183; The trial is registered at EudraCT: 2012-005625-78, ClinicalTrails.gov; NCT02402231. Patients and caregivers provided written informed consent.
FUNDING
The PERMEABLE consortium, supported by ZonMW (456008004), the Swedish Research Council (2018-05619), the Ministry of Education, Science and Sport of the Republic of Slovenia (C3330-19-252012), the German Ministry of Education and Research (BMBF) (FKZ01KU1909A), under the frame of the ERA PerMed JTC 2018 Call. Additional funding in the Appendix.
Sophia Björkander1#
Simon Kebede Merid1#
David Brodin2
Josef Brandström3,4
Fredrik Fagerström-Billai2
Marieke van der Heiden5
Jon R Konradsen4
Michael Kabesch6
Cornelis M van Drunen7
Korneliusz Golebski8,9
Anke H Maitland-van der Zee9
Uroš Potočnik10,11
Susanne J H Vijverberg9
Anna Nopp1,12
Caroline Nilsson1,12
Erik Melén1,12
  1. Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden
  2. Bioinformatics and Expression Core Facility, Karolinska Institutet, Huddinge, Sweden
  3. Clinical Epidemiology Division, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden
  4. Astrid Lindgren Children´s Hospital, Karolinska University Hospital, Stockholm, Sweden
  5. Department of Medical Microbiology and Infection Prevention, University Medical Centre Groningen, University of Groningen, The Netherlands
  6. Department of Pediatric Pneumology and Allergy, University Children’s Hospital Regensburg (KUNO), Regensburg, Germany
  7. Department of Otorhinolaryngology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
  8. Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
  9. Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
  10. Faculty of Medicine, Center for Human Molecular Genetics and Pharmacogenomics, University of Maribor, Maribor, Slovenia
  11. Laboratory for Biochemistry, Molecular Biology and Genomics, Faculty for Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia
  12. Sachs Children and Youth Hospital, Stockholm, Sweden
#Equal contribution