FIGURE LEGENDS
Figure 1. (A, B) Gene ontology (GO) biological
process analysis of upregulated (A) and downregulated (B)genes. The x-axis shows the gene ratio of the overlapping genes of our
gene list with the pathway gene set. The colour bar represents the
adjusted p-value and the circle size is the count of overlapping genes.(C, D) Boxplots display log2 expression values for six
pOIT genes (C : upregulated, D : downregulated) throughout
the treatment protocol at FDR p<0.05. Red box: pOIT start,
green box: Maintenance, blue box: Final. ORA = Over-representation
analysis.
Figure 2. Overlap of 108 genes from the FASTX pOIT study with
the peanut-related genes found in Watson et al . at nominal
p<0.005. The y-axis represents changes in gene expression
between the means at baseline and the four-hour time point of the peanut
challenge in Watson et al , and the x-axis is effect size
estimates from the mixed-effect model in the FASTX pOIT study. The green
colour shows opposite direction, and the pink same direction.