Kevin Plattner (Orcid ID: 0000-0002-2414-9593)
Zahra Gharailoo (Orcid ID: )
Simon Zinkhan (Orcid ID: )
Paul Engeroff (Orcid ID: 0000-0002-3409-512X)
Martin Bachmann (Orcid ID: 0000-0003-4370-2099)
Monique Vogel (Orcid ID: 0000-0002-5219-4033)
Title: IgE glycans promote IgG anti-IgE autoantibodies
that facilitate IgE serum clearance via CD23
Authors: Kevin Plattner1, Zahra
Gharailoo1, Simon Zinkhan1, Paul
Engeroff, Martin F. Bachmann1,2 and Monique
Vogel1*
1Department of Biomedical Research Bern (DBMR),
University Hospital for Rheumatology, Immunology, and Allergology,
University of Bern, Bern, Switzerland.
2Nuffield Department of Medicine, The Jenner
Institute, University of Oxford, Oxford, UK.
*Correspondence to monique.vogel@dbmr.unibe.ch
Competing interests: M. F. Bachmann is a shareholder and board
member of Saiba and Saiba animal health AG. All other authors declare no
conflict of interest.
Author Contributions: K.P. designed, performed and interpreted
experiments. Z.G. and S.Z helped performing experiments. M.F.B., and
M.V. supervised, designed and interpreted experiments. K.P. and M.V.
wrote the manuscript.
Funding: This project was supported by funding from the
following grants: SNF grant 310030_179165/1 to PD Dr. Monique Vogel;
SNF grant 310039_185114 to Martin F. Bachmann