Figures and Tables
Table 1. Baseline characteristics of patients. AH adenoid
hypertrophy, AR allergic rhinitis, * Chi-square, ** Mann Whitney U test.
Figure 1. Novel classification system of adenoids based on
appearance. (A) Edematous-type adenoids. (A’) Edematous type, the tissue
structure was loose, had edema, was accompanied by dilation and
congestion of small vessels. (B) Common-type adenoids. (B’) Common type,
the whole structure was consistent with that of lymphoid tissue. (C)
Fibrous-type adenoids. (C’) Fibrous type, the dense fibrous connective
tissue hyperplasia between lymphoid tissues. Among the 44 cases of AH
without AR, 42 (95.45%) of adenoids were found to be the common type
(D). Among the 106 cases of AH with AR, 72 (67.92%) of adenoids were
found to be of the edematous type (E).
Figure 2 : The morphology and age of adenoids after surgical
treatment. (A) Of the 101 cases of adenoid tissue, 30 (30%) were the
edematous type, 57 (56.44%) were the common type, and 13 (13%) were
the fibrous type. (B) The age of edematous type was 59.77 ± 4.052,
common type was 64.26 ± 3.366, and fibrous type was 81.77 ± 7.122. There
was a significant difference in the age between edematous type and
fibrous type (*P < 0.05).
Figure 3 : Expression of leukotriene receptors and
glucocorticoid receptors in the adenoid tissues of different types. (A)
Immunohistochemical staining showed that the edematous type had a higher
eosinophil count with larger nuclei and red cytoplasm than the common
type and fibrous type. CysLTR1 was expressed in brown granules in all
three types of adenoid tissues. CGR-α and CGR-β were highly expressed in
the edematous type, with a lower expression in the common type and
fibrous type. (B) Western blot showed that CysLTR1 and CysLTR2 were
expressed in all three types of adenoid tissues, and the difference in
expression was not statistically significant. CGR-α was mainly expressed
in the edematous type, which was significantly different from that in
common type and fibrous type.
Figure 4 : The relationship between eosinophil count in the
adenoid tissue and blood and allergic history. (A) The eosinophil count
in the edematous type was higher than that in the common type (P< 0.01). (B) There was a positive correlation between the
eosinophil count in the adenoid tissue and in the blood
(r2 = 0.1023, P < 0.01). (C) There
was no significant difference in the number of eosinophils in the
adenoid tissue and the history of allergic disease.