Figure 2: Representative gross images of the subcutaneous pocket- A) Images show remodeling of the ECM envelope over time at 2, 13, and 26 weeks with increasing levels of vascularization. B) Comparison images from the CIED without envelope implant sites at 13 and 26 weeks show similar thickening of connective tissue but lower vascularization levels and a flipped device at 26 weeks.