Figure 1. Epitope mapping difference plot between PRN and
PRN/mAb (1-6, 3-3, 3-5, 3-16, 3-21, and 3-4) complexes. Red dashed lines
represent the 1.1 Da threshold and the blue dashed lines represent 3σ.
The epitopes are highlighted in coloured stars according to the mAbs
tested and are also coded in the three-dimensional structure with the
corresponding colours.