Figure 3. Relationships between global (genome-wide) CpG observed/expected ratio (O/E), genome size and fish species lifespan. Pearson correlations are given for: A. genome size in gigabase pairs (Gbp) and known lifespan; B. genome size and global CpG O/E and; C. global CpG O/E and known lifespan. Diamond-shaped points indicate species from the Sebastes genus, circles indicate all other species. D. Shows the interaction between global CpG O/E and genome size on known lifespan as predicted by generalised linear modelling (formula shown in the top left), where shaded areas indicate confidence intervals. The figure indicates that the relationship between known lifespan and CpG O/E is dependent on genome size.