• Machine learning was applied (again) to functional connectivity fMRI data \citep{28478510}.
  • Too few neuroimaging studies investigate functional neuroanatomy using focal chemical effects as stimuli. A very compelling study used positron emission tomography (PET) to investigate the regionally specific effects of focal GPe disinhibition on  downstream cortical activity \citep{27989846}. The GABAA antagonist bicuculline was injected into different regions of the macaque external globus pallidus (GPe) that previous studies had previously linked to dyskinesias, hyperactivity, and repetitive behavior. FDG (18F-2-fluoro-2-deoxy-D-glucose) PET was used  ...
  • GABA concentrations in M1/S1 by MR spectroscopy, and TMS measures putatively influenced by GABA, in the same (control) subjects \citep{28284797}.
  • \citet{Mills_2017} describe a 22-year-old man with schizophrenia who developed tics on olanzapine after tapering risperidone. The authors are appropriately cautious in presenting this as a possible case of secondary tics, but given that many people with tics are unaware of the diagnosis, and the fact that olanzapine on average effectively treats tics, this case is much more likely to represent a previously undiagnosed primary tic disorder than a side effect of olanzapine.
  • The future of RDoC as discussed by the new director of NIMH (http://www.webcitation.org/6sccx8sIA).