Comorbidities

An online anonymous survey was answered by 441 primary caregivers of in total 490 children with pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS). A high frequency of medical and psychiatric comorbidities was reported along with a high frequency of autoimmune and psychiatric conditions in family members and elevated levels of stress among caregivers  (INSERT REF  O'Dor SL, Homayoun S, Downer OM, Hamel MA, Zagaroli JS, Williams KA. A Survey of Demographics, Symptom Course, Family History, and Barriers to Treatment in Children with Pediatric Acute-Onset Neuropsychiatric Disorders and Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections. J Child Adolesc Psychopharmacol. 2022 Nov;32(9):476-487. doi: 10.1089/cap.2022.0063. PMID: 36383096.)