Conclusions
After AF ablation, there is a significant asymmetrical reduction of the
LAA ostial area that was independent of LVEF and LAEF changes. LAA
ostial area was larger in patients with HFrEF, and in patients with
“cauliflower” LAA morphology. Larger LAA ostial area was associated
with greater LA and LAA volume, and with lower LAEF and LA strain.
Remodeling of the LAA after AF ablation may help account for reduced
risk of stroke and increased cardiac function. Future studies are needed
to elucidate underlying mechanisms and explore clinical implications.