Study population
In the FMF study there were 168,966 singleton pregnancies with a live
fetus at 11+0 to 13+6 weeks without
major abnormalities that delivered at ≥24 weeks of gestation. In
addition, there were 5,406 (3.1% of the total) that were lost to follow
up. The characteristics of the study population are summarized in Table
1. The pregnancies included 4,272 that developed PE, 4,344 that
developed GH and 160,350 that did not develop either PE or GH. In the
women of black racial origin, compared to white women, there was a
higher median weight, higher incidence of PE and GH, chronic
hypertension, type 2 diabetes mellitus and SLE or APS, and higher
incidence of PE and SGA in a previous pregnancy, and lower incidence of
conception by use assisted reproductive technologies and lower incidence
of nulliparity. In the women of South Asian racial origin, compared to
white women, there was a higher incidence of preterm PE, chronic
hypertension, type 2 diabetes mellitus and SLE or APS, conception byin vitro fertilisation and higher incidence of SGA in a previous
pregnancy. In the women of East Asian racial origin, compared to white
women, there was a lower median weight, lower incidence of GH, smoking,
and incidence of PE in a previous pregnancy and higher incidence of
diabetes mellitus type 2 and previous SGA.