Clinical message
Left ventricular non compaction (LVNC) is a structural abnormality of the left ventricular myocardium of unknown cause. It occurs in isolation or associated with neuromuscular disorders (NMDs). However, its association with jSLE was rarely described. Herein, We reported one of the rare, documented cases of a girl with LVNC associated jSLE with a past history of Hashimoto’s thyroiditis. The association between jSLE, and LVNC requires further research in order to find the probable mechanism joining both entities.