Email of the authors:
Balasubramanian Ganesh (BG): niedrbganesh@gmail.com
Thangarasu Rajakumar (TR):
rajkumar18388@gmail.com
Sridharan Vasumathy (SV):vasumathysridharan@gmail.com
Sridharan Sowmya (SS):sowmyasrithar@gmail.com
Natesan Manikandan (NM): maninatesan87@gmail.com
Harpreet Kaur (HK): kaurh.hq@icmr.gov.in
Abstract: (293 words)
The world is now experiencing the catastrophe of global pandemic
’COVID-19’, most serious public health crises in this century. Recently,
another virus named “Cat Que Virus” (CQV) seems to be causing its
terrible repercussions in the worlds’ largest populous country ‘China’,
the origin of SARS-CoV during 2002-2003, and the current pandemic
SARS-CoV-2 since December 2019. Recently, the presence of IgG antibody
among two persons in the state of Karnataka for CQV was reported in
India, the worlds’ second-largest populous country. This means the virus
is in circulation in the sub-continent. The presence of the vector
mosquitoes (Aedes species, Culex species) and the ambient climatic
conditions suitable for vector breeding in the country needs to be taken
into account while planning to implement holistic strategies appropriate
for control and preventive measures. “One Health approach” is the
topmost option covering humans, animals/vectors and the environment to
curb the spread/transmission of infectious diseases in general. It is
also necessary to study the transmission dynamics and pattern of this
emerging virus, its life cycle, the natural reservoir of the virus, the
intermediate host and the accidental host with respect South-East Asia,
so that necessary remedial action can be planned well before an
epidemic. At present, the outbreak of CQV is certainly a warning to the
general population around the world. Considering the global imminent
health threats posed by CQV, there is an urgent need for active
surveillance, monitoring, effective vaccination, and a standard
treatment modality of this disease. Given the epidemiological aspect of
CQV, control and prevention measures are essential to stop the spread of
the virus. At present, there is no information available on CQV;
however, this current review article has covered the required data,
which will be helpful to control the spread of the CQV.
Keywords: Cat Que Virus; Orthobunyaviruses ; Vector-borne
infection; Tropical nations; Public health; Global threat;
1. Introduction: (1875 words)
The world is now facing one of the most destructive pandemics ever
recorded. Panic of death due to Corona Virus Disease-2019 (COVID-19) is
all around the world and under the influence of this outbreak, another
dangerous virus called Cat Que Virus (CQV) appears to have had its
dreadful consequences in China. CQV was first identified from the
mosquitoes of Cat Que Commune, Hoai Duc District of Ha Tay Province in
Northern Vietnam during the improved surveillance activities for
Japanese Encephalitis Virus (JEV), as well as surveys for arbovirus
activity in regions where Acute Encephalitis Syndrome (AES) cases had
occurred during the period of 2004 causing morbidity and mortality among
children due to acute febrile illness and non-JEV AES. Several people in
the world have been reported infected so far, and this outbreak is
gradually beginning to spread in India as well.The findings of the
recent study conducted by the ICMR-National Institute of Virology (NIV),
Punereported that 2 out of 883 human serum samples had anti-CQV IgG
antibodies. This indicates that these two individuals have been infected
by the virus at some point in time. In specific, CQV spreads through
pigs and species of mosquitoes known asAedesandCulex (Ae. aegypti, Cx. quinquefasciatus, and Cx.
tritaeniorhynchus ).Both of these life forms exist in India and are
vulnerable to CQV. CQV can cause diseases such as meningitis, acute
febrile illness, and pediatric encephalitis to humans (Shete et al.,
2020).