Introduction:
The epidemics and pandemics of human infectious diseases have always been around for thousands of years. In the meanwhile, viruses have caused significant problems that have remained hazardous outbreaks [1].The pandemic of Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) with a quickly universal spread [2, 3]. SARS-CoV-2 can involve multiple organs of the body such as respiratory, gastrointestinal, skeletomuscular, and neurologic systems [4]. Severe diseases arose only in 14% of patients especially in persons with comorbidities including higher age, hypertension, diabetes mellitus, and obesity, cardiac and chronic respiratory diseases [1, 5]. Nasopharyngeal swab and lower respiratory tract specimen can be used for COVID-19 diagnosis [5]. The co-infection of COID-19 with other endemic and local pathogens could detain the suitable medicine of the causative agent [4]. Brucellosis is an endemic zoonosis disease and an important public health issue in most developing countries such as Iran [3, 6]. Consumption of raw milk, unpasteurized dairy products, and inhalation of infected droplets can lead to brucellosis [7]. Typical symptoms of brucellosis including fever, malaise, and arthralgia can be similar to COVID-19 symptoms. The common laboratory findings of these infections are thrombocytopenia and leukopenia [3, 7]. In this article, a suspected COVID-19 case was hospitalized then who was finally diagnosed with co-infection with brucellosis and discussed.