Acknowledgements
The authors would like to thank Pavel Dagorov and his workshop team (FHNW) for hollow fiber filter modification and Sebastian Schneider and Silvia Pavone (FHNW) for supporting experimental work on perfusion processes. The authors also thank the entire Levitronix team for support, especially Knut Kuss for valuable input. Dominik Schieman, Paul Niepold and David Garcia (Novartis) kindly sponsored the manufacturing scale filter module. Moreover, the authors would like to acknowledge specifically the Bioprocess Sciences (BPS) team of Merck Serono SA (an affiliate of Merck KGaA) for material and analytical support and for valuable discussions and support throughout the project, especially Alexandre Châtelin and the analytical team.