Abstract
Objectives:The purpose of this study was to improve the diagnostic rate by
analyzing the data of the clinical, radiology and pathological of
Allergic fungal rhinosinusitis (AFRS).
Method: The data of patients with chronic sinusitis (CRS)
treated in our center from January 2015 to December 2020 were analyzed.
The discharged patients diagnosed with AFRS and the suspected cases in
the description of radiology or surgical records were reviewed, combined
with specific
immunoglobulin
E (IgE) examination, they were divided into three groups: AFRS,
suspected AFRS and fungal ball sinusitis (FBS). The participants’
demographic, laboratory data and clinical characteristics were all
analyzed.
Results: 631 patients with non-invasive fungal sinusitis were
treated in the past 6 years. 29 cases of AFRS, 69 cases of suspected
AFRS and 533 cases of FBS. A total of 98 confirmed and suspected AFRS
cases were identified, with an average age of 34.3 years, 25 cases with
bone erosion. The significant differences were observed in age,
eosinophils or basophils percentage, total serum IgE, CT Lund-Mackay
score, combined with allergic rhinitis, asthma and hypoolfactory between
AFRS or confirmed AFRS and FBS, but no differences between AFRS and
suspected AFRS.
Conclusion: AFRS may be misdiagnosed due to the low detection
of fungi. In order to reduce the recurrence of the disease, we can
consider the diagnosis of AFRS for patients with clinical, radiology and
immunological characteristics consistent with AFRS but without fungal
etiology.