Materials and methods
Our research had been reviewed by the ethics
committee of our hospital before initiating this
retrospective study; the present work was produced in conjunction with
the STROBE guidelines for reporting on cohort studies.The medical record
information management system was used to record ‘sinusitis’ as the
keyword to search for discharge diagnosis. All patients treated at our
center were collected between January 2015 and December 2020. Read the
patient’s discharge records and operation records. When the case was
diagnosed as FBS, AFRS or with allergic mucin described in the operation
records, we re-read the data of radiographic imaging, laboratory, and
pathological section, and
re-diagnose according to Bent-Kuhn diagnostic
criteria2. All cases were divided into three groups: A
for AFRS: The patients were diagnosed according to Bent-Kuhn diagnostic
criteria. B for suspect AFRS: The
characteristics of clinical, radiology and allergic mucin were in
accordance with the Bent-Kuhn criteria, and fungal specific IgE was
positive, but no fungal evidence. C for FBS: Fungus ball infection
clinical manifestation, typical radiology, the description of fungus
lump in surgical records, and the fungal examination in
histopathological sections were positive.
The data of three groups were collected, including gender, age, number
of recurrences, side and number of sinus, bone erosion, the peripheral
blood eosinophils and basophils percentage, galactomannan test, serum
total IgE, pathological findings of fungi, and whether conbain with
allergic rhinitis, asthma, or olfactory hypothyroidism. The difference
in the above items between group A and group B, group A and group C, and
group B and group C were compared.