Figure legends :
Figure 1: Flow diagram of patients with hepatic presentations of LCH
Figure 2: Algorithm to approach a patient with LCH associated chronic
liver disease based on stage of liver disease (category 1 and category
2)
Figure 3: : Liver biopsies demonstrating features of large duct
obstructive cholangiopathy with portal fibrous expansion and bile
ductular proliferation (A & B, H&E). Liver biopsy with cluster of
Langerhans cells (arrow, C, H&E). CD1a immunostaining of Langerhans
cells (D). External surface of an explant liver with greenish
discolouration and micronodularity (E). Cut surface of an explant liver
with marked greenish discolouration and multiple bile ducts with biliary
sludge (arrow, F). Light microscopy image displaying cirrhosis (H&E,
G). Ductopenia in an explant liver (H&E, H)