Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP. Table 1. Available Outcome Measures from the Included Studies on Different Treatment Modalities used in the Surgical Procedures for RRP.
NO Study, Year Study Design time\follow-up time No. RRP Onset (JoRRP /AoRRP) Treatment Modality (instruments used in the surgical procedures) Sample Size Age(years), Mean (SD) or Median (Range) Mean Number of Procedures complications(n) Complications Rate (%)
NO.1 HOCK. 2022[15]. Restrospective 1999~2019,>12months 112(68:44) microdebrider 49 35.5 [23.5] 17.3 [24.1] 22 44.89
KTP laser 42 36.1 [24.9] 19.6 [32] 23 54.76
CO2 laser 21 39.4 [22.7] 15.5 [14.5] 8 38.10
NO.2 HUNG. 2021[24] Restrospective 2013~2019, 5-69months 16(0:16) KTP laser 16 38.5(23-73] 4.94 3 18.17
NO.3 Wenbin.2006[6] Restrospective 2001-2005 33(33:0) microdebrider 14 3.8(0.8~8) 4.71 0 0
NO.4 PATEL.2003[5] Prospective cohort study(non-randomized). 1998-2001 17(17:0) microdebrider 15 (1.5-14) 3.33 0 0
17(17:0) CO2 laser 17 (1.5-14) 7.47 0 0
NO.5 EL-BITAR. 2002[25] Restrospective 1999-2000 10(10:0) microdebrider 16 3.75 3.13 0 0
10(10:0) CO2 laser 16 3.75 1.44 5 31.25
NO.6 Miller.2019[26]. Restrospective 2005-2012 17(0/17) microdebrider 17 62(30~86) 13.53 0 0
NO.7 Hao-Chun Hu.2017[27] Restrospective 2014-2015, 2-21months 6(0/6) CO2 laser 6 56(29-83] 1.67 0 0
NO.8 Papaspyrou. 2016[9]. Restrospective 2006-2016, 12-120 months 37(NA) CO2 laser 37 52(2~77 ) 1.22 3 8.11
NO.9 Del Signore.2016[28] Restrospective 2008~2012 34(0/34) KTP laser 34 49(17-90) NA 3 8.82
NO.10 Kuet.2013[29] Restrospective 2007–2010, 12–40 months 19(0/19) KTP laser 19 16–84 NA 0 0
NO.11 Ossoff.1991[30] Restrospective 1986-1990, 43.2months 22(14/8) CO2 laser 22 NA 4.78 3 13.63
NO.12 Araki.2019[31] prospective validation study 2015-2017, 13–37 months 7(0/7) CO2 laser 7 45.8(30-36) 1.71 0 0
NO.13 Papaioannou.2018[14] Retrospective 1983-2014. 76.8months 106(27/79) CO2 laser 44 0.25-11.6 2.16 7 15.91
NO.14 Zhao.2007[32] Retrospective 2000-2005, 6-60months 30(NA) CO2 laser 30 0.5-78 NA 7 23.33
NO.15 Preuss.2007[16] Retrospective 1963 to 1993, 6-295 months 194(59/135) CO2 laser 64 35.9(0.17-81) 2.14 8 12.50
NO.16 Burns.2007[33] prospective assessment 2005-2006 37(0/37) KTP laser 37 23-73 1.49 0 0
NO.17 Rees.2005[34] Retrospective 2002-2004, 24months 50(50/0) microdebrider 50 <14 NA 0 0
NO.18 Dedo.2001[35] Retrospective 1973-2000 227(NA) CO2 lasers 227 NA NA 79 34.80
NO.19 Cui.2001[36] Retrospective 1993-1998,18-72months 60(60/0) CO2 lasers 60 2.8(0.67-10) 5.58 24 40.00
NO.20 Shah.1994[37] Retrospective ~1994 54(54/0) CO2 lasers 54 NA 3.98 6 11.11
Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available. Abbreviations: CO2, carbon dioxide; KTP, potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available.