Abbreviations: CO2, carbon dioxide; KTP,
potassium-titanyl-phosphate; AoRRP, adult-onset recurrent respiratory
papillomatosis (RRP);JoRRP, juvenile-onset RRP; NA, not available.
The weighted complication rate for microdebrider treatment of RRP was
0.03 (95% CI 0.00-0.21, n = 6, I2 = 91.08%, P <0.1). The weighted
complication rate for CO2 laser treatment was 0.16 (95% CI 0.09-0.25, n
=14, I2= 79.19%, p <0.1). The weighted complication rate for KTP
laser treatment was 0.04 (95% CI 0.00-0.14, n =4, I2=67.76%, p=0.03).
Of the included literature, only three studies reported intraoperative
complications, all occurring during surgery using CO2 lasers.
Complications in these procedures included vocal cord edema in 3
patients and intratracheal burning in one case. As for postoperative
delayed complications, included cases, reported anterior commissure web,
vocal scar, glottic stenosis, granulation polyp and atrophy. Among the
postoperative complications reported, the largest number of cases was
anterior commissure web, regardless
of the surgical method used. Specific information on complication types
and complication rates is presented in Figure 2.and Table 3.