Table 4. Clinical chorioamnionitis predictors of adverse neonatal outcomes in study participants with chorioamnionitis. Crude and adjusted Odds ratios with corresponding 95% confidence intervals.
Chorioamnionitis = 500 Chorioamnionitis = 500
No neonatal infection N 448 Neonatal infectiona N 52 OR (95% CI) Crude OR (95% CI)b Adjusted
No temp. ≥38.0°C 48 (10.7) 6 (11.5) Reference (1.0) Reference (1.0)
≥ 1 temp 38.0-38.9°C 400 (89.3) 46 (88.5) 0.92 (0.37-2.27) 0.90 (0.36-2.23)
Temp 38.0-38.9°C ≥30 minutes 211 (47.1) 31 (59.6) 1.66 (0.92-2.97) 1.58 (0.88-2.85)
≥ 1 temp ≥ 39.0°C 104 (23.2) 10 (19.2) 0.79 (0.38-1.62) 0.80 (0.39-1.66)
Leukocyte count first
≤14.7 137/395 (34.7) 12/48 (25.0) Reference (1.0) Reference (1.0)
14.8-19.2 121/395 (30.6) 24/48 (50.0) 2.26 (1.09-4.72) 2.14 (1.02-4.49)
>19.2 137/395 (34.7) 12/48 (25.0) 1.00 (0.43-2.30) 0.90 (0.39-2.10)
Leukocytes, highest
≤17.0 131/395 (33.2) 15/48 (31.3) Reference (1.0) Reference (1.0)
17.1-21.5 131/395 (33.2) 18/48 (37.5) 1.2 (0.58-2.48) 1.07 (0.51-2.23)
>21.5 133/395 (33.7) 15/48 (31.3) 0.98 (0.46-2.09) 0.90 (0.42-1.93)
CRP first
≤33 128/384 (33.3) 15/47 (31.9) Reference (1.0) Reference (1.0)
34-109 132/384 (34.4) 13/47 (27.7) 0.84 (0.39-1.84) 0.79 (0.36-1.74)
>109 124/384 (32.3) 19/47 (40.4) 1.31 (0.64-2.69) 1.24 (0.60-2.56)
CRP, highest
≤147 136/384 (35.4) 7/47 (14.9) Reference (1.0) Reference (1.0)
148-232 129/384 (33.6) 16/47 (34.1) 2.41 (0.96-6.05) 2.36 (0.94-5.95)
>232 119/384 (31.0) 24/47 (51.1) 3.92 (1.63-9.42) 4.01 (1.66-9.68)
Fetal tachycardia 291/441 (66.0) 41/52 (78.9) 1.91 (0.96-3.84) 1.99 (0.99-4.00)
Positive cervical culture 113/316 (35.7) 20/36 (55.6) 2.25 (1.20-4.51) 2.22 (1.10-4.48)