Clinical applicability
Betahistine is one of the most used empirical treatments, requiring a better scientific approach. To the best of our knowledge, this randomized clinical trial is the first reliable study to test this treatment for this purpose. Our results reveal that this drug is ineffective for primary tinnitus in adults, therefore, its large-scale use is likely to be of no benefit to patients. We believe that this result can avoid the negative impact of the use of ineffective treatments by these patients.