Conclusion
Betahistine was ineffective when compared to the placebo in the treatment of the primary tinnitus.
Figure Legend:
Figure 1. Consolidated Standards of Reporting Trials (CONSORT) Participant Flow Diagram
Numbers of study participants approached, enrolled and followed up for 3 months. Ineligibility may be due to more than 1 reason.
Figure 2. Box and Whisker Plot of Tinnitus Handicap Inventory (THI) Change
Distribution of THI change before and after intervention between both study groups (31 participants in each group). The ends of the boxes indicate the upper and lower quartile, the middle lines the median, and the whiskers the minimum and maximum values.
Figure 3. CGI-I Response Summary per Study Group
The distribution of Clinical Global Impression Improvement (CGI-I) response between both study groups (31 participants in each group). The bars indicate the number of participants per CGI-I scale.
Table 1. Demographics and THI Response of Study Participantsa