Main Findings
We performed a single-center, retrospective review of 307 patients
treated with amiodarone for a minimum of one month as a part of a
rhythm-control strategy that culminated in catheter ablation for AF. We
hypothesized that failure of rhythm control on amiodarone would predict
increased rates of AF recurrence following ablation, but found that our
hypothesis was incorrect; patients who did and did not achieve rhythm
control on amiodarone prior to PVI had equivalent rates of freedom from
recurrent atrial arrhythmia following ablation, suggesting that response
to amiodarone is not an adequate litmus test for considering PVI in AF
patients.