Early phase (n =22) Late phase (n =22)
P-value
Echocardiographic findings Echocardiographic findings Echocardiographic findings Echocardiographic findings
LV LV LV LV
4D-LV end-diastolic volume index, cc/m2 39.2±5.7 44.7±7.6 0.003*
4D-LV end-systolic volume index, cc/m2 14.5 (13.5-17.1) 16.4 (13.5-18.6) 0.27
4D-Stroke volume index, cc/m2 22.6±5.7 29.4±5.4 <0.001*
4D LV Ejection fraction, % 61.5 (55-65) 64.4 (59-69) 0.009*
4D LV Global Longitudinal Strain, % -20 (-21.4- -19) -23.9 (-25.3- -21.9) 0.004*
4D LV Global Circumferential Strain, % -28.7±4.31 -29.1±5.2 0.81
4D LV Global Radial Strain, % 39.6 (36.3-43.6) 43.3 (39.9-46.9) 0.13
Twist, degree 11.2±8.6 8.8±7.3 0.38
Torsion, degree/cm 1.3 (0.7-2.3) 1.2 (0.2-2.3) 0.61
Diastolic parameters Diastolic parameters Diastolic parameters Diastolic parameters
E wave velocity, m/s 0.8 (0.6-0.9) 0.7 (0.6-0.8) 0.25
A wave velocity, m/s 0.6 (0.5-0.7) 0.6 (0.5-0.7) 0.27
Septal E’ velocity, cm/s 10.5 (8-12.1) 8 (10-11.5) 0.34
Lateral E’ velocity, cm/s 13.5 (11.52-16) 13 (11.5-15) 0.46
RV RV RV RV
4D-RV end diastolic volume index, cc/m2 34.6±7.4 30.6±9 0.14
4D-RV end-systolic volume index, cc/m2 14.5±3.9 12.1±3.5 0.01*
4D-RV Ejection fraction, % 59.4 (54.9-60.8) 57 (54.7-61.8) 0.88
4D-RV FAC, % 47.2 (42.3-52.2) 36.4 (31.1-45) 0.002*
4D-RV free wall Global Longitudinal Strain, % -28.3±3.5 -28.6±5.1 0.79
TAPSE, mm 22.5 (19.1-24.2) 23 (21-25) 0.55
RVsm, cm/sec 12.8 (12-14.1) 12.1 (12-13.2) 0.65
RV Strain rate, s-1 -1.31±0.29 -1.30±0.22 0.91
LA LA LA LA
LA end-systolic volume, cc 29.8 (21.4-42.8) 33 (27.7-41.5) 0.11
LA peak Strain rate, s-1 1.7±0.3 1.5±0.5 0.17
RA RA RA RA
RA peak Strain rate, s-1 1.8 (1.3-1.9) 1.3 (1.2-1.5) 0.007
Systolic PAP, mm Hg 25 (21.5-28.5) 25 (25-30) 0.06