Early phase (n =41) Late phase (n =41)
P-value
Echocardiographic findings Echocardiographic findings Echocardiographic findings Echocardiographic findings
LV LV LV LV
4D-LV end-diastolic volume index, cc/m2 39.9±8.7 44.6±10 0.02*
4D-LV end-systolic volume index, cc/m2 14.9 (13-17.5) 15.3 (12.5-19.8) 0.29
4D-Stroke volume index, cc/m2 24.7±4.1 29.7±7.05 <0.001*
4D LV Ejection fraction, % 61.9 (59.8-64.5) 63.8(58.2-68.9) 0.02*
4D LV Global Longitudinal Strain, % -22.3(-23.5- -21.3) -21.2 (-24.3- -19.6) 0.51
4D LV Global Circumferential Strain, % -28.7±3.8 -30.4±5.1 0.18
4D LV Global Radial Strain, % 41.4 (37.6-43.9) 41.5 (39.6-46.1) 0.41
Twist, degree 13.5±9.7 12.5±9.1 0.66
Torsion, degree/cm 1.6 (0.9-2.3) 1.4 (0.8-2.2) 0.61
Diastolic parameters Diastolic parameters Diastolic parameters Diastolic parameters
E wave velocity, m/s 0.7 (0.7-0.8) 0.7 (0.6-0.8) 0.68
A wave velocity, m/s 0.5 (0.5-0.6) 0.6 (0.5-0.7) 0.44
Septal E’ velocity, cm/s 10.7 (8-12) 10 (9-12) 0.26
Lateral E’ velocity, cm/s 14.7 (12.7-16.7) 13.2 (12-16) 0.006*
RV RV RV RV
4D-RV end diastolic volume index, cc/m2 33.6±8.8 29.3±28.3 0.06
4D-RV end-systolic volume index, cc/m2 13.6±4.5 12.5±3.4 0.21
4D-RV Ejection fraction, % 58.1 (53.5-62.5) 57.9 (54.5-62.7) 0.455
4D-RV FAC, % 46.6 (43.6-53) 39.7 (25-43) <0.001*
4D-RV free wall Global Longitudinal Strain, % -32.3±4.6 -28.8±5.8 0.002*
TAPSE, mm 21 (19-24) 23(20-25) 0.09
RVsm, cm/sec 13 (12-14) 12 (11-13) 0.12
RV Strain rate, s-1 -1.19±0.44 -1.31±0.29 0.14
LA LA LA LA
LA end-systolic volume, cc 35 (27.7-44.3) 37.8 (31.8-44.5) 0.19
LA peak Strain rate, s-1 1.4±0.3 1.31±0.32 0.01*
RA RA RA RA
RA peak Strain rate, s-1 1.50 (1.20-1.92) 1.30 (1.07-1.50) 0.09
Systolic PAP, mm Hg 25.00 (22-29.00) 25.00 (21.75-27.50) 0.80