Clinically severe COVID-19
When 22 patients in the severe intensity COVID-19 group were observed in late echocardiography, 4DLVEDVI increased significantly (39.2±5.7 cc/m2 vs. 44.7±7.6 cc/m2, p-value=0.003), as did 4DLVSVI (22.6±5.7 cc/m2 vs. 29.4±5.4 cc/m2, p-value<0.001) and LVEF (61.5% [55-65] vs. 64.45% [59-69], p-value=0.009), respectively. The LVGLS was increased significantly over the follow-up period (-20% [-21.4- -19] vs. -23.9% [-25.3–21.9], p-value=0.004). At both follow-up appointments, all diastolic indices, including E and A wave velocity, and lateral and septal E’ velocity, were within normal range and not significantly changed. RVFWGLS showed no statistically significant change during the study period (-28.3% ±3.5 vs. -28.6% ±5.1, p-value=0.79). The RVESVI decreased significantly in the late echocardiogram (14.5%±3.9 vs. 12.1%±3.5, p-value=0.01). The RV-FAC (47.2% [42.3-52.2] vs. 36.4% [31.1-45], p-value=0.002) showed a significant decrease and TAPSE (22.5 mm [19.1-24.2] vs. 23 mm [21-25], p-value= 0.55), was not significantly different but both altered within the normal range. None of the LA indices, including LAESV and LA peak SR, changed significantly. RA peak strain rate significantly decreased (1.8% [1.3-1.9] vs. 1.3% [1.2-1.5], p-value=0.007). (Table 3)