Eltrombopag group Control group ALL patients P value
Rate at 3 Mo
No. of patients 66 49 115
Response-no. (%)
CR 20(30.3) 4(8.2) 24(20.9) 0.004
OR 42(63.6) 23(46.9 66(57.4) 0.074
Rate at 6 Mo
No. of patients 66 49 115
Response-no. (%)
CR 33(50.0) 5(10.2) 38(33.0) <0.001
OR 47(71.2) 28(57.1) 75(65.2) 0.117
Rate at 12 Mo
No. of patients 66 49 115
Response-no. (%)
CR 34(51.5) 21(42.9) 55(47.8) 0.358
OR 47(71.2) 32(65.3) 79(68.7) 0.499
Rate at the end of follow-up
Relapse 5(7.6) 2(4.1) 7(6.1) 0.703
Death 2(3.0) 2(4.1) 4(3.5)
Clonal evolution 0(0) 1(2.0) 1(0.9)
Lost to follow up 0(0.0) 10(20.4) 10(8.7)