Characteristics Number of patients CENPN CENPN χ2value P value
negative(%) positive(%)
Gender 0.723 0.395
Male 53 14(26.4) 39(73.6)
Female 23 4(17.4) 19(82.6)
Age 0.158 0.691
<65(years) 24 5(20.8) 19(79.2)
≥65(years) 52 13(25.0) 39(75.0)
Tumor size(cm) 1.653 0.198
<6 45 13(28.9) 32(71.1)
≥6 31 5(16.1) 26(83.9)
Differentiation 0.487 0.485
Well-Moderate 41 11(26.8) 30(73.2)
poor 35 7(20.0) 28(80.0)
Depth of invasion 8.507 0.004
T1+T2 25 11(44.0) 14(56.0)
T3+T4 51 7(13.7) 44(86.3)
TNM stage 7.991 0.005
Ⅰ+Ⅱ 37 14(37.8) 23(62.2)
Ⅲ+Ⅳ 39 4(10.3) 35(89.7)
Nodal status 4.353 0.037
N0 23 9(39.1) 14(60.9)
N1 N2 N3 53 9(17.0) 44(83.0)