Satellite data show substantial drops in nitrogen dioxide (NO2) during COVID-19 physical distancing. To attribute NO2 changes to NOx emissions changes over short timescales, one must account for meteorological effects. We find that meteorological patterns were especially favorable for low NO2 in much of the U.S. in spring 2020, complicating comparisons with spring 2019. Meteorological variations between years can cause column NO2 differences of ~15% over monthly timescales. After accounting for sun angle and meteorological considerations, we calculate that NO2 drops ranged between 9.2 – 43.4% among twenty cities in North America, with a median of 21.6%. Of the studied cities, largest NO2 drops (>30%) were in San Jose, Los Angeles, and Toronto, and smallest drops (<12%) were in Miami, Minneapolis, and Dallas. These normalized NO2 changes can be used to highlight locations with greater activity changes and better understand the sources contributing to adverse air quality in each city.