All cultures (n = 2,103) All cultures (n = 2,103) Cultures with pathogenic organisma (n = 282, 13.4%) Cultures with pathogenic organisma (n = 282, 13.4%) Cultures without pathogenic organism (n = 1,821, 86.6%) Cultures without pathogenic organism (n = 1,821, 86.6%)
p-valueb
Collection Details
Specimen source Tracheostomy aspirate
Bronchoalveolar lavage
1,394 709 (66.3 %) (33.7%) 246 36 (87.2%) (12.8%) 1,148 673 (63.0%) (37.0%)
<0.001
Child’s age at culture collection 1.2 [0.7, 2.1] 0.7 [0.5, 1.3] 1.3 [0.7, 2.1] <0.001
Diagnosis of acute respiratory infectionc at culture collectiond 630 (33.7%) 129 (45.7%) 501 (31.6%) <0.001
Encounter type at culture collection Hospital admission
Office visit
Specimen collection only
1,864 145 94 (88.6%) (6.9%) (4.5%) 264 13 5 (93.6%) (4.6%) (1.8%) 1,600 132 89 (87.9%) (7.2%) (4.9%)
0.31
Department at culture collection Acute care
Bronchoscopy Suite
Critical care
Emergency Department
Pulmonology, Otolaryngology Clinic
Other Clinice
1,171 364 196 128 113 131 (55.7%) (17.3%) (9.3%) (6.1%) (5.4%) (6.3%) 191 8 58 6 13 6 (67.7%) (2.8%) (20.6%) (2.1%) (4.6%) (2.1%) 980 356 138 122 100 125 (53.8%) (19.5%) (7.6%) (6.7%) (5.5%) (6.9%)
<0.001
Culture Results
Pathogenic organisms identifieda Overall
By species
Pseudomonas aeruginosa
Staphylococcus aureus
Klebsiella pneumoniae
Serratia marscescens
Moraxella catarrhalis
Escherichia coli
Klebsiella oxytocya
Stenotrophomonas maltophilia
Enterobacter species
Group A Streptococcus
Haemophilus influenzae
Streptococcus pneumoniae
282 107 98 39 30 20 13 11 9 9 8 6 2 (13.4%) (5.1%) (4.7%) (1.9%) (1.4%) (1.0%) (0.6%) (0.5%) (0.4%) (0.4%) (0.4%) (0.3%) (0.1%) 282 107 98 39 30 20 13 11 9 9 8 6 2 (100%) (37.9%) (34.8%) (13.8%) (10.6%) (7.1%) (4.6%) (3.9%) (3.2%) (3.2%) (2.8%) (2.1%) (0.7%) – – – – – –
Polymicrobial growth 83 (3.9%) 83 (29.4%)
WBCs quantified on gram stainf Many
Moderate
Few
Very few
None
806 454 401 289 135 (38.3%) (21.6%) (19.1%) (13.7%) (6.4%) 144 62 44 20 10 (51.1%) (22.0%) (15.6%) (7.1%) (3.5%) 662 392 357 269 125 (36.4%) (21.5%) (19.6%) (14.8%) (6.9%)
<0.001