References
1. Wright MFA, Wallis C. Investigation and management of the long-term ventilated premature infant. Early Hum Dev . Nov 2018;126:10-17. doi:10.1016/j.earlhumdev.2018.08.015
2. Ralser E, Mueller W, Haberland C, et al. Rehospitalization in the first 2 years of life in children born preterm. Acta Paediatr . Jan 2012;101(1):e1-5. doi:10.1111/j.1651-2227.2011.02404.x
3. Akangire G, Taylor JB, McAnany S, et al. Respiratory, growth, and survival outcomes of infants with tracheostomy and ventilator dependence. Pediatr Res . Aug 2021;90(2):381-389. doi:10.1038/s41390-020-01183-x
4. Watters K, O’Neill M, Zhu H, Graham RJ, Hall M, Berry J. Two-year mortality, complications, and healthcare use in children with medicaid following tracheostomy. Laryngoscope . Nov 2016;126(11):2611-2617. doi:10.1002/lary.25972
5. Tracy MK, Berkelhamer SK. Bronchopulmonary Dysplasia and Pulmonary Outcomes of Prematurity. Pediatr Ann . Apr 1 2019;48(4):e148-e153. doi:10.3928/19382359-20190325-03
6. Cristea AI, Carroll AE, Davis SD, Swigonski NL, Ackerman VL. Outcomes of children with severe bronchopulmonary dysplasia who were ventilator dependent at home. Pediatrics . Sep 2013;132(3):e727-34. doi:10.1542/peds.2012-2990
7. Overman AE, Liu M, Kurachek SC, et al. Tracheostomy for infants requiring prolonged mechanical ventilation: 10 years’ experience.Pediatrics . May 2013;131(5):e1491-6. doi:10.1542/peds.2012-1943
8. Edwards JD, Kun SS, Keens TG. Outcomes and causes of death in children on home mechanical ventilation via tracheostomy: an institutional and literature review. J Pediatr . Dec 2010;157(6):955-959 e2. doi:10.1016/j.jpeds.2010.06.012
9. Akangire G, Manimtim W. Tracheostomy in infants with severe bronchopulmonary dysplasia: A review. Front Pediatr . 2022;10:1066367. doi:10.3389/fped.2022.1066367
10. Watters KF. Tracheostomy in Infants and Children. Respir Care . Jun 2017;62(6):799-825. doi:10.4187/respcare.05366
11. Akangire G, Lachica C, Noel-MacDonnell J, et al. Outcomes of infants with severe bronchopulmonary dysplasia who received tracheostomy and home ventilation. Pediatr Pulmonol . Mar 2023;58(3):753-762. doi:10.1002/ppul.26248
12. House M, Nathan A, Bhuiyan MAN, Ahlfeld SK. Morbidity and respiratory outcomes in infants requiring tracheostomy for severe bronchopulmonary dysplasia. Pediatr Pulmonol . Aug 2021;56(8):2589-2596. doi:10.1002/ppul.25455
13. Russell CJ, Simon TD, Mamey MR, Newth CJL, Neely MN. Pseudomonas aeruginosa and post-tracheotomy bacterial respiratory tract infection readmissions. Pediatr Pulmonol . Sep 2017;52(9):1212-1218. doi:10.1002/ppul.23716
14. Konstan MW, Morgan WJ, Butler SM, et al. Risk factors for rate of decline in forced expiratory volume in one second in children and adolescents with cystic fibrosis. J Pediatr . Aug 2007;151(2):134-9, 139.e1. doi:10.1016/j.jpeds.2007.03.006
15. Blanchard AC, Waters VJ. Microbiology of Cystic Fibrosis Airway Disease. Semin Respir Crit Care Med . Dec 2019;40(6):727-736. doi:10.1055/s-0039-1698464
16. Razvi S, Quittell L, Sewall A, Quinton H, Marshall B, Saiman L. Respiratory microbiology of patients with cystic fibrosis in the United States, 1995 to 2005. Chest . Dec 2009;136(6):1554-1560. doi:10.1378/chest.09-0132
17. Sanders DB, Bittner RC, Rosenfeld M, Redding GJ, Goss CH. Pulmonary exacerbations are associated with subsequent FEV1 decline in both adults and children with cystic fibrosis. Pediatr Pulmonol . Apr 2011;46(4):393-400. doi:10.1002/ppul.21374
18. Amadori A, Antonelli A, Balteri I, Schreiber A, Bugiani M, De Rose V. Recurrent exacerbations affect FEV(1) decline in adult patients with cystic fibrosis. Respir Med . Mar 2009;103(3):407-13. doi:10.1016/j.rmed.2008.09.024
19. Sanders CD, Guimbellot JS, Muhlebach MS, Lin FC, Gilligan P, Esther CR, Jr. Tracheostomy in children: Epidemiology and clinical outcomes.Pediatr Pulmonol . Sep 2018;53(9):1269-1275. doi:10.1002/ppul.24071
20. Russell CJ, Simon TD, Neely MN. Development of Chronic Pseudomonas aeruginosa-Positive Respiratory Cultures in Children with Tracheostomy.Lung . Dec 2019;197(6):811-817. doi:10.1007/s00408-019-00285-6
21. Steuart R, Ale GB, Woolums A, et al. Respiratory culture organism isolation and test characteristics in children with tracheostomies with and without acute respiratory infection. Pediatr Pulmonol . Feb 7 2023;doi:10.1002/ppul.26349
22. Feudtner C, Feinstein JA, Zhong W, Hall M, Dai D. Pediatric complex chronic conditions classification system version 2: updated for ICD-10 and complex medical technology dependence and transplantation. BMC pediatrics . 2014;14:199. doi:10.1186/1471-2431-14-199
23. Lewis TR, Kielt MJ, Walker VP, et al. Association of Racial Disparities With In-Hospital Outcomes in Severe Bronchopulmonary Dysplasia. JAMA pediatrics . Sep 1 2022;176(9):852-859. doi:10.1001/jamapediatrics.2022.2663
24. Team RC. R: A language and environment for statistical computing.MSOR connections . 2014;1
25. Sanders DB, Bittner RC, Rosenfeld M, Hoffman LR, Redding GJ, Goss CH. Failure to recover to baseline pulmonary function after cystic fibrosis pulmonary exacerbation. Am J Respir Crit Care Med . Sep 1 2010;182(5):627-32. doi:10.1164/rccm.200909-1421OC
26. Sanders DB, Hoffman LR, Emerson J, et al. Return of FEV1 after pulmonary exacerbation in children with cystic fibrosis. Pediatr Pulmonol . Feb 2010;45(2):127-34. doi:10.1002/ppul.21117
27. de Boer K, Vandemheen KL, Tullis E, et al. Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis.Thorax . Aug 2011;66(8):680-5. doi:10.1136/thx.2011.161117
28. Ritchie AI, Wedzicha JA. Definition, Causes, Pathogenesis, and Consequences of Chronic Obstructive Pulmonary Disease Exacerbations.Clin Chest Med . Sep 2020;41(3):421-438. doi:10.1016/j.ccm.2020.06.007
29. Wedzicha JA, Seemungal TA. COPD exacerbations: defining their cause and prevention. Lancet . Sep 1 2007;370(9589):786-96. doi:10.1016/s0140-6736(07)61382-8
30. Dang X, Kang Y, Wang X, et al. Frequent exacerbators of chronic obstructive pulmonary disease have distinguishable sputum microbiome signatures during clinical stability. Front Microbiol . 2022;13:1037037. doi:10.3389/fmicb.2022.1037037
31. Maddux AB, Mourani PM, Miller K, et al. Identifying Long-Term Morbidities and Health Trajectories After Prolonged Mechanical Ventilation in Children Using State All Payer Claims Data.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies . Apr 1 2022;23(4):e189-e198. doi:10.1097/pcc.0000000000002909
32. Kompare M, Weinberger M. Protracted bacterial bronchitis in young children: association with airway malacia. J Pediatr . Jan 2012;160(1):88-92. doi:10.1016/j.jpeds.2011.06.049
33. de Vries JJV, Chang AB, Marchant JM. Comparison of bronchoscopy and bronchoalveolar lavage findings in three types of suppurative lung disease. Pediatr Pulmonol . Apr 2018;53(4):467-474. doi:10.1002/ppul.23952
34. Teplitzky TB, Kou YF, Bozkanat KM, Johnson RF, Chorney SR. Pathogenic bacteria in bronchoalveolar lavage cultures and pediatric laryngotracheal reconstruction outcomes. Pediatr Pulmonol . Jan 31 2023;doi:10.1002/ppul.26338
35. Fujitani S, Sun HY, Yu VL, Weingarten JA. Pneumonia due to Pseudomonas aeruginosa: part I: epidemiology, clinical diagnosis, and source. Chest . Apr 2011;139(4):909-919. doi:10.1378/chest.10-0166
36. Metersky ML, Frei CR, Mortensen EM. Predictors of Pseudomonas and methicillin-resistant Staphylococcus aureus in hospitalized patients with healthcare-associated pneumonia. Respirology . Jan 2016;21(1):157-63. doi:10.1111/resp.12651
37. Idigo AJ, Wells JM, Brown ML, et al. Clinical risk factors for admission with Pseudomonas and multidrug-resistant Pseudomonas community-acquired pneumonia. Antimicrob Resist Infect Control . Jul 14 2022;11(1):95. doi:10.1186/s13756-022-01137-4
38. Tiffany CR, Bäumler AJ. Dysbiosis: from fiction to function.Am J Physiol Gastrointest Liver Physiol . Nov 1 2019;317(5):G602-g608. doi:10.1152/ajpgi.00230.2019
39. Hanada S, Pirzadeh M, Carver KY, Deng JC. Respiratory Viral Infection-Induced Microbiome Alterations and Secondary Bacterial Pneumonia. Front Immunol . 2018;9:2640. doi:10.3389/fimmu.2018.02640
40. Gauguet S, D’Ortona S, Ahnger-Pier K, et al. Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia.Infect Immun . Oct 2015;83(10):4003-14. doi:10.1128/iai.00037-15
41. Schuijt TJ, Lankelma JM, Scicluna BP, et al. The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia. Gut . Apr 2016;65(4):575-83. doi:10.1136/gutjnl-2015-309728
42. Niederman MS, Ferranti RD, Zeigler A, Merrill WW, Reynolds HY. Respiratory infection complicating long-term tracheostomy. The implication of persistent gram-negative tracheobronchial colonization.Chest . Jan 1984;85(1):39-44.
43. Thorburn K, Jardine M, Taylor N, Reilly N, Sarginson RE, van Saene HK. Antibiotic-resistant bacteria and infection in children with cerebral palsy requiring mechanical ventilation. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies . Mar 2009;10(2):222-6. doi:10.1097/PCC.0b013e31819368ac
44. Warniment A, Steuart R, Rodean J, et al. Variation in Bacterial Respiratory Culture Results in Children With Neurologic Impairment.Hospital pediatrics . Nov 2021;11(11):e326-e333. doi:10.1542/hpeds.2020-005314
45. Gallego M, Pomares X, Espasa M, et al. Pseudomonas aeruginosa isolates in severe chronic obstructive pulmonary disease: characterization and risk factors. BMC pulmonary medicine . Jun 26 2014;14:103. doi:10.1186/1471-2466-14-103
46. Ashkenazi-Hoffnung L, Ari A, Bilavsky E, Scheuerman O, Amir J, Prais D. Pseudomonas aeruginosa identified as a key pathogen in hospitalised children with aspiration pneumonia and a high aspiration risk.Acta Paediatr . Dec 2016;105(12):e588-e592. doi:10.1111/apa.13523
47. Borgatta B, Lagunes L, Imbiscuso AT, Larrosa MN, Lujàn M, Rello J. Infections in intensive care unit adult patients harboring multidrug-resistant Pseudomonas aeruginosa: implications for prevention and therapy. Eur J Clin Microbiol Infect Dis . Jul 2017;36(7):1097-1104. doi:10.1007/s10096-016-2894-3
48. Manuck TA. Racial and ethnic differences in preterm birth: A complex, multifactorial problem. Semin Perinatol . Dec 2017;41(8):511-518. doi:10.1053/j.semperi.2017.08.010
49. 2022 March of Dimes Report Card . 2022. https://www.marchofdimes.org/report-card
50. McCaleb R, Warren RH, Willis D, Maples HD, Bai S, O’Brien CE. Description of Respiratory Microbiology of Children With Long-Term Tracheostomies. Respir Care . Apr 2016;61(4):447-52. doi:10.4187/respcare.03518