Adjuvant surgery and radiotherapy
A total of eight patients with liver or brain metastases underwent
adjuvant surgery to extirpate drug-resistant lesions. The surgical
procedure included pulmonary lobectomy (n=5), resection of
drug-resistant lesions in the liver (n=1), uterus (n=1), and
ophthalmologic surgery (n=1), respectively. Local interventional surgery
was performed in three patients to manage bleeding. Of the 11 GTN
patients with liver or brain metastases, 8 (8/11, 72.7%) received 11
adjuvant surgical treatments.
No patients received whole-brain radiation therapy but three patients
had stereotactic radiotherapy for residual brain metastases at the end
of treatment (Table 2).